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Orthopedics and Osteoporosis 2018
N o v e m b e r 2 9 - 3 0 , 2 0 1 8
Am s t e r d a m , N e t h e r l a n d s
Page 37
Journal of Clinical & Experimental Orthopaedics
ISSN: 2471-8416
E u r o p e a n C o n f e r e n c e o n
Orthopedics and
Osteoporosis
T
he bone scan findings of the Paget’s disease are well established and
documented and considered to be the hall mark findings of the disease.
It usually presents as asymmetrical, diffuse and dense skeletal hot spots
with irregular margins. It is characterized by the typical flame appearance of
the marrow involvement. The earliest attempt to characterize the hot spots
by means of the triple phase bone scan is by dynamic curve analysis. That
is done by calculating the blood pool ratio and the skeletal ratio. No useful
clinical application could be derived due to the cumbersome process. Hence
in five cases of Paget’s disease that encountered in our case collection the
scintimetric characterization of the skeletal hot spots by Dr V Siva’s retention
ratio is applied. The triple phase bone scan is followed by 24 hr repeat whole
body bone scan from the time of radiopharmaceutical injection. The maximum
counts at the focal hotspots in 4 hr and 24 hr images are obtained using
region ratio protocol and tabulated. The Dr V Siva’s retention ratio is calculated
by dividing the 4 hr counts by 24 counts. Fig.1 shows the sample image of
scintimetric characterization in a case of Paget’s disease. All the cases showed
plethora of values ranging from 1 to 30 defying the cut off values of benign,
degenerative and neoplastic categories. Thus the Paget’s disease is a water
loo for the Dr V Siva’s retention ratio and the cause for it is elaborated.
Biography
V Siva Subramaniyan is a Doctoral Research Scholar pursuing
his research in the area of Scintimetric characterization in the
University SSSIHL, Prasanthinilayam under the guidance of
Prof K Venkataramaniah. He is a Senior Radiologist, Consultant
Nuclear Medicine Physician and Imaging Specialist. He was
awarded Dr Ashok Mukherjee Gold Medal for the best young
Radiologist of the country in the year 1999 for his research
work by the Indian Radiological and Imaging Association-IRIA.
He was invited to present his research work as poster in the
IPET 2015 organized by IAEA at Vienna. He is pursuing his
research and academic work. He has delivered more than 75
presentations, 9 thesis guidance and 10 publications to his
credit.
drvsiva@outlook.comScintimetric characterization of skeletal hot spots in Paget’s
disease
V Siva Subramaniyan and K V enkataramaniah
SSSIHL, India
V Siva Subramaniyanand et al., J Clin Exp Orthop 2018, Volume: 4
DOI: 10.4172/2471-8416-C1-005