occupational-health-2018-keynote

3 / 7

Journal of Nursing and Health Studies
ISSN: 2574-2825
May 28-29, 2018
London, UK
Occupational Health 2018
Page 15
4th Edition of International Conference on
Occupational Health and
Safety
Inoccupationalmedicine
occupational physician needs tools for an objective evaluation
of psychoscial stress. Those tools could be questionnaires
such as visual analogue scale of stress or jod-demand-control
questionnaire of Karasek, which can be useful to detect the
most at-risk workers. Those tools to evaluate stress could also
be biomarkers of stress. For example, we were the first team to
propose saliva DHEAS as a reliable biomarker of stress. Then,
stress can also be physiological. Main physiological stress are a
mental stress, a physical stress (exercise), insufficient nutritional
intake, or a sleep deprivation. Emergency physicians are a model
of stress because they combine all types of stress. They are in
a particular psychosocial context and they are confronted to
death, they have sometimes to run, they cannot eat when they
want and sometimes do not eat during 24 hours, they also
cannot sleep. We will present main articles published from the
Job stress study which compared several putative biomarkers
of stress through different types of night shifts, through a shift-
randomized controlled design. Main biomarkers of stress are
heart rate and heart rate variability, as well as pro-inflammatory
cytokines. We demonstrated several incidences of maximal HR
during shifts combined with a high cardiac strain, as well as a
poor heart rate variability and a systematic inflammation. The
24-hour consecutive shifts exhibited the highest changes in
biomarkers of stress. We also highlighted a prolonged response
to the night shifts with the highest response three days after the
shifts. The main explaining factor of the increase of biomarkers
of stresswas life-and-death emergencies. Therefore, we suggest
that emergency physicians limit their exposure to 24-hour shifts
and be cautious on the third day after the shift.
Biography
Frédéric Dutheil is a Professor in Medicine; Medical Doctor in Occupational
Health; Physiologist and Researcher at University Hospital of Clermont-Fer-
rand (CHU) and; a Clinical Fellow of Australian Catholic University. He is
member of Laboratory of Metabolic Adaptations to exercise in clinical and
pathological conditions (AME2P-EA 3533) from 2006 to 2015, his work on
biomarkers of stress led him to the creation and the Head of Physiological
and Psychosocial Stress team at UMR CNRS 6024. He is the Scientist of
Wittyfit, a software designed to improve health of workers, through a per-
sonalized and individualized feedback of their health, taking into account
job characteristics. He is now aiming at building tools for objective mea-
sures of stress.
Physiological and psychosocial stress -
Biomarkers of stress
Frédéric Dutheil
1University Hospital of Clermont-Ferrand (CHU), Occupational and Preventive
Medicine,F‑63000 Clermont‑Ferrand, France
2University Hospital of Clermont-Ferrand (CHU), Emergency department,
F‑63000 Clermont‑Ferrand, France
3Université Clermont Auvergne, CNRS,LaPSCo, Physiological and Psychosocial
Stress, F‑63000 Clermont‑Ferrand, France
4Australian Catholic University, Faculty of Health, Melbourne, VIC 3065, Australia
5WittyFit, F‑75000 Paris, France
Frédéric Dutheil, J Nurs Health Stud 2018, Volume 3
DOI: 10.21767/2574-2825-C2-004