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Volume 4, Issue 2 American Journal of Ethnomedicine
ISSN 2348-9502
Natural Products Congress & World Pharma Congress 2017
October 16-18, 2017
3rd World Congress on
NATURAL PRODUCTS CHEMISTRY AND RESEARCH
&
12th WORLD PHARMA CONGRESS
October 16-18, 2017 Budapest, Hungary
Sesquiterpene lactones from Artemisia L. endemic species
Gayane Atazhanova1 and Sergazy M Adekenov2
National Academy of Sciences of the Republic of Kazakhstan, Kazakhstan
JSC “International Research and Production Holding Phytochemistry”, Republic of Kazakhstan
Plants from Artemisia L. genus belonging to Asteraceae Dumort. family are one of the main sources of sesquiterpene lactones.
Ninety species of wormwood grow in the territory of Kazakhstan, 20 of which are endemic and considered as potential sources
of novel, previously unexplored natural compounds, especially sesquiterpene lactones. We have carried out the chemical analysis
of 11 endemic plant species from Artemisia L. genus for the first time, they are as follows: Artemisia aralensis Krasch., Artemisia
cina Berg., Artemisia filatovii A. Kuprijanov sp. nova, Artemisia glabella Kar. et Kir., Artemisia halophila Krasch., Artemisia
hippolyti Butkov, Artemisia karatavica Krasch. et Abol., Artemisia radicans A. Kuprijanov sp. nova, Artemisia saissanica (Krasch.)
Filat., Artemisia semiarida (Krasch. et Lavr.) Filat., Artemisia succulenta Ldb. Fl. Alt. From 11 endemic species of Artemisia L.
25 sesquiterpene lactones were determined. In doing so, 7 new sesquiterpene lactones were isolated, and the structures of their
molecules elucidated by means of modern physical, chemical and spectral methods (IR-, PMR-, 13С NMR, mass-), including X-ray
analysis.
Gayane Atazhanova et al., American Journal of Ethnomedicine, 4:2
DOI: 10.21767/2348-9502-C1-002