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Infectious Diseases
and STD-AIDS
Infectious Diseases and STD-AIDS 2018
Journal of Transmitted Diseases and Immunity
ISSN 2471-8084
A p r i l 2 6 - 2 7 , 2 0 1 8
R o m e , I t a l y
Page 34
Background
: Blood stream infection (BSI) varies from self-limiting infections
to life threatening sepsis. This study was conducted to determine bacterial
agents causing BSI and their antimicrobial resistance profiles.
Methods:
A retrospective study was conducted on febrile patients suspected
for blood stream infections from March 2013 to January 2015 at Bahir Dar
Regional Health Research Laboratory Center (BRHRL), Ethiopia. According
to standard operational procedure for blood culture, venous blood samples
were collected aseptically and processed with conventional blood culture.
Antimicrobial susceptibility tests were performed using Kirby-Bauer disc
diffusion methods.
Results:
From 561 blood specimens, aerobic bacterial growth was observed
on 220 (39.2%) samples. Age groups were statistically associated with BSI
(P=0.001). Gram negative isolates constituted 115 (52.3%).
Staphylococcus
aureus with 22.7% was the predominant isolates followed by Coagulase-
negative
Staphylococcus
(15.9%),
Klebsiella pneumoniae
(15.9%),
Escherichia
coli
(8.6%),
Pseudomonas aeruginosa
(6.8%) and
Acinetobacter
species (5.9%).
The overall range of drug resistance for Gram positive bacteria were 7% to 61%
and for Gram negatives 6.9% to 82.6%. Among the Gram positive bacteria, high
resistance levels were observed against Penicillin (61%) and Oxacillin (52.9%).
The Gram negative organisms showed 66 to 82.6% resistance to Ampicillin,
Ceftriaxone and Trimethoprim-sulfamethoxazole.
Conclusions:
The present study revealed that blood stream infection linked
with high levels of drug resistance is a significant health problem. Hence,
early identification of bacterial pathogens and determining their antibiotic
susceptibility could play key role for appropriate treatment of blood stream
infection.
Biography
Derese Hailu has completed his BS degree in Addis Ababa Uni-
versity and Second-degree MS degree in Medical Microbiology
at University of Gondar. He has nine years of work experience.
From 2016-2017, he was working as Laboratory Directorate Di-
rector in Amhara Public Health Institute (APHI). Currently, he is
working as Researcher in APHI. He has taken different trainings
and short courses. Especially, he has taken TOT trainings pro-
vided by American Society for Microbiology (ASM).
deresehailu86@gmail.comBlood stream infection and antibiogram among patients referred to
Bahir Dar Regional Health Research Laboratory Center Ethiopia: A
Retrospective Study
Derese Hailu
1
, Bayeh Abera
2
, Gashaw Yitayew
1
, Daniel
Mekonnin
2
and Awoke Derbie
2
1
Bahir Dar Regional Health Research Laboratory Center, Ethiopia
2
Bahir Dar University, Ethiopia
Derese Hailu et al., J Transm Dis Immun 2018 Volume 2
DOI: 10.21767/2573-0320-C1-002