20 / 26
Immunology 2018
J u l y 0 5 - 0 7 , 2 0 1 8
V i e n n a , A u s t r i a
Page 57
Journal of Clinical Immunology and Allergy
ISSN 2471-304X
1 5
t h
I n t e r n a t i o n a l C o n f e r e n c e o n
Immunology
B
acteriophages are ubiquitous, specific viruses. They attack sensitive
bacteria. Elements of their capsids bind to specific molecules on the target
host surface. Bacteria that do not have such a receptor can’t be attacked. Their
use as therapeutics of infectious diseases of animals and people refers to the
times before antibiotic therapy. The ability of phages to kill bacterial cells is
the basis of the idea of using them as therapeutic agents. Innate immunity is
rarely discussed in terms of phage therapy. New research has demonstrated
that the host immune response is an important factor in the effectiveness of
phage therapy. In recent years, there have been reports about the interaction
of bacteriophages with the immune system. It mainly concern people. Our
studies have demonstrated the immunomodulatory effect of bacteriophages
on lower vertebrates.
Biography
Andrzej K Siwicki is Head of Department, Microbiology and
Clinical Immunology, Faculty of Veterinary Medicine, University
of Warmia and Mazury; Department of Pathology and
Immunology, IFI in Olsztyn, Poland. He is the author of over
500 original papers in reputed journals and about 200 scientific
communications (index-h 32, index of citation: 4502). His
fields of interest are modulation of defence mechanisms and
protection against diseases by natural and synthetic products in
animals, influence of pollutants on the cell-mediated immunity
and restoration of immunity after suppression induced by
xenobiotics. He developed a new possibility in the comparative
immunotoxicology for control of effect of xenobiotics and
pharmaceutical products on the defence mechanisms and
protection against diseases. He attended scientific missions in
USA, Japan, France and Israel, was a Co-ordinator of USDA and
FAO projects and he is Professor conferring of 14 PhDs and 4
DScs.
siwicki@uwm.edu.plInfluence of bacteriophages on the immune system: a
comparative study
A K Siwicki
1
, P Schulz
1
, J Dastych
2
and E Wojcik
2
1
University of Warmia and Mazury in Olsztyn, Poland
2
Proteon Pharmaceuticals SA, Poland
A K Siwicki et al., Insights Allergy Asthma Bronchitis 2018, Volume: 4
DOI: 10.21767/2471-304X-C1-002