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Pediatrics Conference 2018
Journal of Pediatric Care
ISSN: 2471-805X
Page 45
March 26-27, 2018
Edinburgh, Scotland
2
nd
Edition of International Congress on
Pediatrics
T
he present study aimed to assess the prognostic value of
early amplitude-integrated electroencephalogram (aEEG) in
late preterm infants who were born at a gestational age between
34 0/7 and 36 6/7 weeks for the prediction of neurobehavioral
development. Late preterm infants (n = 170) with normal, mild,
and severe asphyxia underwent continuous recording of aEEG
for 4–6 h starting 6–8 h after delivery. The recordings were
analyzed for background pattern, sleep-wake cycle (SWC), and
seizures. Survivors were assessed at 18 months by neurological
examination and Bayley Scales of infant development II. The
incidence of adverse neurological outcome in the asphyxia
group was significantly higher than in the normal group. For late
preterm infants in the asphyxia group, abnormal aEEG pattern had
a predictive potential of neurological outcomes with sensitivity
of 78.57% (specificity 87.80%; positive predictive value [PPV]
68.75%; negative predictive value [NPV] 92.31%; power 85.45%).
Non-SWC and intermediate SWC significantly were increased
(25.45% and 52.73%, respectively) in the asphyxia group vs. the
normal group. SWC pattern had neurological prognosis value
in the asphyxia group with sensitivity of 64.29 % (specificity
87.80%; PPV 64.29%; NPV 87.80%; power 81.82%). Early aEEG
patterns are important determinants of long-term prognosis of
neurodevelopmental outcome in asphyxiated late preterm infants.
cm_jiang@126.comEarly amplitude-integrated EEG monitoring 6h after birth
predicts long-term neurodevelopment of asphyxiated late
preterm infants
Chun Ming Jiang
Hangzhou First People’s Hospital - Nanjing Medical University, China
J Pediatr Care, Volume 4
DOI: 10.21767/2471-805X-C1-006