Notes:
Volume 4
Journal of Pediatric Care
ISSN: 2471-805X
Page 20
JOINT EVENT
Pediatric Critical Care 2018 &
World Pediatrics 2018
October 18- 20 , 2018
October 18- 20, 2018 Warsaw, Poland
&
6
th
International Conference on
25
th
World Pediatrics Conference
Pediatric Critical Care and Emergency Medicine
Ayush Shrivastava, J Pediatr Care 2018, Volume 4
DOI: 10.21767/2471-805X-C4-014
Nucleated red blood cells as marker of perinatal asphyxia
Ayush Shrivastava
Jawaharlal Nehru Medical College, DMIMS, India
W
orld Health Organization (WHO) has defined perinatal asphyxia as a failure to initiate and sustain breathing at birth.
Hypoxic ischemic encephalopathy (HIE) is one of the most common complications in an asphyxiated neonate because
of its serious long term neuromotor sequelae among the survivors. Nucleated red blood cells (NRBC) count in umbilical cord
of newborns has been suggested as a sign of birth asphyxia. As the present markers are not accurate in diagnosis and assessing
the severity of fetal asphyxia, this study was undertaken to find the values of NRBCs in normal and asphyxiated neonates and
the correlation of NRBCs with birth asphyxia. 80 neonates with asphyxia along with 80 healthy newborns were undertaken
for two years study period. Maternal and neonatal information was recorded followed by clinical and laboratory evaluation.
An NRBC level was determined per hundred white blood cells (WBC). Post discharge, immediate follow-up of asphyxiated
infants was performed. Neonates were divided into two groups, with favorable and unfavorable outcome based on discharge
or death. We observed that NRBC count with more than 10 per hundred WBC per cubic millimeter, had sensitivity of 88.75%
and specificity of 100% in predicting complications of asphyxia. We demonstrate that NRBC per hundred WBC can be used as
prognostic marker for neonatal asphyxia, which in combination with the severity of asphyxia can be co-related with high infant
mortality, immediate outcome and complications of asphyxia.
Biography
Ayush Shrivastava has completed his MD at Datta Meghe Institute of Medical Science (Deemed University). He is working as a Senior Resident and intrested in
research projects. He is involved in pediatrics clinical practice since 2015. He has more than three years of undergraduate teaching experience. He has attended
more than 50 conferences and workshops in India, organized and presented posters in national and international conferences.
ayushrivastava@gmail.com