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Volume 4
Journal of Pediatric Care
ISSN: 2471-805X
Page 58
JOINT EVENT
May 07-08, 2018 Frankfurt, Germany
&
3
rd
International Conference on
Pediatrics and Pediatric Surgery
22
nd
Edition of International Conference on
Neonatology and Perinatology
Neonatal thrombocytopenia: Its associated risk factors and outcome in NICU in a tertiary hospital in
Nepal
Bishow Bandhu Bagale
Bharatpur Hospital, Nepal
T
hrombocytopenia is a frequently encountered hematological abnormality in neonatal intensive care unit (NICU). It is
associated with various maternal and neonatal risk factors and the incidence varies greatly depending upon the population
studies. In a retrospective study, 412 neonates who were admitted in Bharatpur Hospital NICU during November 2016 till
October 2017 were included in the study. Depending upon the values thrombocytopenia was categorized into mild, moderate
and severe types. Incidence of thrombocytopenia was determined along with maternal and neonatal risk factors associated
with it. Maternal risk factors like pregnancy induced hypertension (PIH), diabetes, maternal immune thrombocytopenic
purpura (ITP), eclampsia, drug use and neonatal risk factors like sepsis, asphyxia, intrauterine growth restriction (IUGR),
prematurity, necrotizing enterocolitis (NEC) were analyzed. The incidence of neonatal thrombocytopenia was found to be 74
in 412 neonates which comprised approximately 18% neonates admitted in NICU. Early onset thrombocytopenia occurring
within 72 hours comprised 91.8% while late onset thrombocytopenia occurring after 72 hours comprised 8.2% of total
thrombocytopenia. 58.1% (43) comprised of mild, 29.7% (22) moderate and 12.2% (9) severe thrombocytopenia. The major
risk factors among the neonates were sepsis, asphyxia, IUGR and prematurity while gestational diabetes mellitus (GDM), PIH
and maternal ITP were the common maternal risk factors contributing to the neonatal thrombocytopenia. However, there was
no correlation found between sex and race with the occurrence of thrombocytopenia. Neonatal thrombocytopenia accounted
for 18% of neonates which were admitted in the NICU. Significant neonatal risk factors were asphyxia and sepsis and maternal
risk factors were PIH and diabetes.
drbbandhhu@gmail.comJ Pediatr Care, Volume 4
DOI: 10.21767/2471-805X-C2-009