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Pain Management 2018
Internal Medicine 2018 International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X Page 27
March 26-28, 2018
Vienna, Austria
JOINT EVENT
7 t h E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Internal Medicine and Patient Care
&
6 t h E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Pain Management
Volume 4
S tudies indicate that <50% of Polymyalgia Rheumatica (PMR)
patients receive glucocorticoid-inducedosteoporosis
(GIOP) prevention when nearly all should be prescribed bone
protective therapy (BPT) according to current guidelines.
Our objective is to determine if PMR patients in Cork
are adequately protected from GIOP by examining bone
densitometry (DXA) scan results, BPT use, and adherence
to guidelines.PMR patients with a documented history of
glucocorticoid use who underwent a DXA scan at CUH from
01/01/2016 and 27/10/2017 were included in the analysis.
Patient demographic information, use of BPT, and DXA
T-scores were obtained from chart review. 153 patients were
identified, of whom 69% were female. 73 (47.7%) were taking
BPT consistent with current guidelines and 42 (27.5%) were
not taking any BPT. At the most recent DXA scan, 42 (27.5%)
had normal BMD, 84 (54.9%) were osteopenic, and 27 (17.6%)
were osteoporotic. The mean T-score of patients receiving BPT,
-1.76, is significantly lower than the mean T-score of patients
not receiving BPT, -1.41 (p=0.04). In a regression analysis,
BMI and BPT were significantly associated with osteoporosis
or osteopenia (p=0.007 and p=0.049 respectively). In 91
individuals who underwent ≥2 DXA scans, patients not receiving
bisphosphonates were more likely to have BMD loss over time
(p=0.022). Despite guideline recommendations, many patients
are not prescribed adequate BPT, demonstrated by a high rate
of osteoporosis and osteopenia. The results suggest that
PMR patients in Cork are not optimally protected from GIOP,
uncovering an opportunity to improve the current management
of PMR.
Biography
Tara Swami is a final year medical student at University College Cork in Ire-
land. She completed a Bachelor of Science at McGill University in Montreal,
Canada and a Master of Biotechnology in Toronto, Canada and has a keen
interest in Rheumatology.
The Effectiveness of Glucocorticoid-Induced Osteoporosis
Prevention in Polymyalgia Rheumatica Patients.
Tara Swami and Dr. Catherine Molloy
University College Cork, Ireland
Tara Swami et al., Int J Anesth Pain Med 2018, Volume 4
DOI: 10.21767/2471-982X-C1-002