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Journal of Transmitted Diseases and Immunity
ISSN: 2573-0320
Volume 4
May 10-11, 2018
Frankfurt, Germany
Immunology Research 2018
Tissue Science 2018
Page 45
JOINT EVENT
2 2 n d E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Immunology and
Evolution of Infectious Diseases
&
1 2 t h E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Tissue Engineering and
Regenerative Medicine
Biological tissue often exhibits extraordinary complexity. For
example, neural tissue comprises large numbers of neurons
with cell-type specific axonal and dendritic arborisation, highly
structured synaptic connectivity, and fine-tuned electrical activity.
A better understanding of how such tissue complexity develops
is often essential for tissue engineering purposes. To this end,
author will present some of his computational models of neural
tissue development, demonstrating how complex structure and
function can be generated based solely on simple genetic rules.
These multi-scale models comprise intracellular as well as
extracellular dynamics in a detailed, physical 3D environment.
In particular, author will elaborate on computational models of
cortical and retinal structure and function, ranging across different
spatial scales. By modelling the biological self-organization of
such tissue, predictions are made and so novel hypotheses are
generated, which can be experimentally validated. Moreover,
these models can inform and guide tissue engineering protocols.
Finally, author will discuss modern computational approaches,
including the BioDynamo software, which is a collaborative project
with project partner CERN Openlab. Overall, author will emphasize
the importance of computer models as a tool to advance tissue
engineering approaches.
Biography
Roman Bauer is an MRC Research Fellow at Institute of Neuroscience-New-
castle University, with joint affiliation with the School of Computing. His re-
search involves computational models to better understand how neural tissue
evolves during development. He received his Bachelor’s and Master’s Degree
in Computational Science and Engineering from ETH Zurich, Switzerland. Af-
terwards, he did his Doctoral studies at Institute for Neuroinformatics (INI)-
ETH and University Zurich, working on simulations of cortical development.
After Postdoctoral work at Newcastle University from 2013 to 2016, he took
up a prestigious MRC fellowship. His research interests include “Neural devel-
opment, neural degeneration, neural disorders, gene regulatory networks and
cryopreservation”.
Computational modelling of neural tissue
growth
Roman Bauer
Newcastle University, UK
Roman Bauer, J Transm Dis Immun 2018, Volume 2
DOI: 10.21767/2573-0320-C2-004