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Immunology 2018
J u l y 0 5 - 0 7 , 2 0 1 8
V i e n n a , A u s t r i a
Page 89
Journal of Clinical Immunology and Allergy
ISSN 2471-304X
1 5
t h
I n t e r n a t i o n a l C o n f e r e n c e o n
Immunology
S
. agalactiae
has been appearing as a vital human pathogen and a gradually important cause of aggressive infections in
immunocompromised adults and older. The aim of the study was to find the effect of inflammatory cytokines (interleukin 2
and 8) and immune reactive molecules (CD79 and CD54 molecules) on pathogenesis of
S. agalactiae
that isolated from aborted
women. A total of 100 aborted women aged between (16 - 42) years, were involved in this study. Placentas specimens were
cultured to isolate the
Streptococcus agalactiae
, the level of cytokine in the serum was measured by commercial ELISA tests,
while CD molecules was estimated by immunohistochemistry assay. Our results showed that there was streptococcal isolates
from placental specimens, specific isolation and identification were done for
S. agalactiae
. Significant difference could be found
in serum levels of inflammatory cytokines (P≤ 0.05) between these two investigated groups (infected and uninfected with
S.
agalactiae
) in addition to high expression for CD79 and CD54 in infected women as compare with non
S. agalactiae
infected
women.
aliscience16@yahoo.comRole of inflammatory cytokines and immune
reactive molecules in pathogenesis of
Streptococcus agalactiae in aborted women
Ali Anok Njum
University of Awsat forat, Iraq
Insights Allergy Asthma Bronchitis 2018, Volume: 4
DOI: 10.21767/2471-304X-C1-003