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Notes:
Volume 3, Issue 2 (Suppl)
Trends in Green chem
ISSN: 2471-9889
Environmental & Green Chemistry 2017
July 24-26, 2017
Page 87
5
th
International Conference on
6
th
International Conference on
July 24-26, 2017 Rome, Italy
Environmental Chemistry and Engineering
Green Chemistry and Technology
&
Green synthesis of chiral imines and their Zn(ll) complexes
Daniela Gutiérrez, Eduardo Brambila, Alejandro Ruíz, Carolina Gutiérrez, Guadalupe Hernández, Gloria E Moreno, Oscar Portillo
and
René Gutiérrez
Universidad Autónoma de Puebla, México
Statement of the Problem:
Nowadays, reactions conducted in the absence of solvents under mild reaction conditions are becoming
an important method in laboratories worldwide as an environment-friendly technique for the efficient syntheses of organic molecules.
The main advantages of solvent-free organic synthesis are shorter reaction times, minimum waste and generally higher yields,
operational simplicity as well as reduction of thermal degradative byproducts along with cleaner work-up.
Methodology:
The preparation of two chiral imines derived from 2-piridylcarboxaldehyde and the optically active primary aromatic
amine (S)-(-)-1-(4-methylphenyl) ethylamine and (S)-(-)-1-(4-metoxyphenyl) ethylamine by solvent-free techniques.
Findings:
The ligands obtained were allowed to coordinate with Zn(II) also under solvent-free conditions affording complexes 1 and
2, respectively. The products were characterized by using spectroscopic techniques (FT-IR, NMR H and C, EI-MS) and the structure
of the Zn(ll) complexes was fully confirmed by X-ray diffraction studies. The antimicrobial activity of the complexes (I)–(III) was
evaluated against Gram positive
(Staphylococcus aureus)
and Gram negative (
E. coli, Pseudomonas aeruginosa
) bacteria, and yeast
(Candida albicans).
Conclusion & Significance:
The complexes were found to possess noteworthy antimicrobial activity.
Figure: Crystal structure of complex 1 and Crystal structure of complex 2
Biography
Daniela Gutiérrez completed her Bachelor’s degree at the Universidad Autónoma de Puebla (México) in 2015. She is pursuing Master’s degree in Biochemistry
and Molecular Biology. Her research interests are the synthesis of metallic complexes by using Green Chemistry methods and their application in the biology field.
danita_13@hotmaill.comDaniela Gutiérrez et al., Trends in Green chem, 3:2
DOI: 10.21767/2471-9889-C1-003