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Dental Treatment 2018 Dentistry and Craniofacial Research
ISSN: 2576-392X Page 28
September 10-11, 2018
Zurich, Switzerland
25th International Conference on
Dental Treatment
Introduction: Diabetes adversely affects the morphology of
buccal mucosa and may compromise tissue function to favours
the occurrence of oral infections and neoplasia. The morphologic
and functional changes in oral mucosa can be studied at the
cellular level by using exfoliative cytology which can help the
diagnosis, with better patient acceptability as it is a painless, non-
invasive and less time-consuming procedure.
Subjects & Methods: A total of 180 patients were included in
the study. Patients were also grouped into the following three
categories for further analysis based on their glycohemoglobin
(GHb) levels: Controlled diabetics (CD) - GHb≤6%, Uncontrolled
diabetics (UCD) - GHb>6% and ≤8% and Non-diabetics (ND) -
GHb>8%.Smearsweretakenfromclinicallynormalbuccalmucosa
of these subjects and stained to look for any abnormalities.
Results: Statistical analysis of the data obtained showed that the
MV of meisels cells from non-diabetic patients was significantly
higher (p=0.008) than cells from diabetic subjects. Percentage
of micronuclei was significantly higher (p=0.00) in uncontrolled
diabetics as compared to controlled diabetics and non-diabetics.
Conclusion: Diabetesmellitus induces definitemorphological and
morphometric changes in the exfoliated buccal mucosal cells.
However, for establishing exfoliative cytology as a diagnostic tool
for diabetes, further studies are required on a larger scale.
Biography
Nandita Shenoy has graduated in 2004 from Yenepoya Dental College with
gold medal for best outgoing student. She completed her post graduate
training from MCODS Manipal in 2008. She joined MCODS Mangalore in
2008 as an Asst. Professor & is currently an Associate Professor in Oral
Medicine and Radiology. Dr. Nandita is having 54 published papers in peer
reviewed journals till date and 2 ICMR grants. She is a firm believer in in-
ter disciplinary interaction and research & have co-authored papers and
conducted research relevant to my specialty along with various depart-
ments like Geriatrics, Diabetology ,Oncology, Pharmacology, Dermatology,
Infectious Diseases, and General Medicine. She have completed advanced
training and certification in CBCT applications and interpretation. She is also
serving as the Radiation Safety officer for MCODS, Mangalore. She is the
recipient of Dentsply proactive junior academician in her specialty.
Buccal smear: A promising tool in the diagnosis of diabetes
mellitus
Nandita Shenoy, Aditya Gupta and Junaid Ahmed
Manipal Academy of Higher Education, India
Nandita Shenoy et al., J Dent Craniofac Res 2018, Volume 3
DOI: 10.21767/2576-392X-C3-008