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Volume 2, Issue 2 (Suppl) Chronic Obstructive Pulmonary Diseases
ISSN: 2572-5548
Page 18
Notes:
August 31-September 01, 2017 Brussels, Belgium
&
International Conference on Chronic Diseases
6th International Conference on Microbial Physiology and Genomics
conferenceseries.com
CO-ORGANIZED EVENT
The Efficacy of Bile Acids in the treatment of Non-alcoholic Steatohepatitis: A 10-year Systematic
Review
Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease which may progress
to non-alcoholic steatohepatitis (NASH). Currently there are no therapeutic strategies for such disease. Only lifestyle
modification through diet and exercise were proven to afford some benefit in patients with NAFLD. No pharmacologic agents
have so far been approved for the treatment of NAFLD or NASH. Therefore, most clinical efforts have been directed at treating
the components of metabolic syndrome, namely obesity, diabetes, hypertension and dyslipedemia. Other interventions are
directed at specific pathways potentially involved in the pathogenesis of NAFLD, such as insulin resistance, oxidative stress,
proinflammatory cytokines, apoptosis, bacterial overgrowth, and angiotensin pathway. This lecture aims to show the potential
of Bile acids as a promising therapeutic option for NAFLD. This is a 10-year Sytematic Review of the effects of Bile Acids on
Non-Alcoholic Fatty Liver Disease (NAFLD). This 10- year review shows that, alongside diet, exercise and weight loss, Bile
Acids may yet prove to be an effective targeted treatment for Non Alcoholic Fatty Liver Disease.
Biography
Professor Higinio T. Mappala is a distinguished physician and gifted medical researcher with 30 years of clinical experience, as well as a prolific communicator and lecturer
in both academic and clinical fora. A board-certified specialist in Internal Medicine with board-certified subspecialties in Gastroenterology, Endoscopy, Clinical Toxicology
and Pharmacology, and Clinical Nutrition. He is University Professor, a Dean of the School of Medicine, and Administrator at the undergraduate, graduate, and postgradu-
ate levels; an author of more than 50 scientific papers. As a prolific lecturer, he has been a Focused lecturer on NAFLD for more than 10 years.
Higinio T Mappala
Jose R. Reyes Memorial Medical Center, Manila, Philippines
Higinio T Mappala, Chron Obstruct Pulmon Dis 2017, 2:2
DOI: 10.21767/2572-5548-C1-001