Topical corticosteroids preparations are commonly used in the treatment of ocular inflammation. For anterior segment inflammation, topical steroids treatment is usually preferred over systemic steroids owing to its safety, convenience, and low risk of systemic side effects. Although serum drug levels are apparently low in patients receiving topical corticosteroids there may be a change in levels of plasma cortisol and adrenocorticotropic hormone. Fukushima et al. showed in two different publications an early effect on serum glucose levels, within hours, after subconjunctival injection of dexamethasone in diabetic and non-diabetic rats and an early transient increase in blood glucose levels on the day of surgery in diabetic patients. Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results. Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.