Colorectal Liver Metastases

Surgical resection remains the gold standard treatment for CLMs, achieving 10-year survival rate of twenty-two during a selected group of patients. However, only 20% of CLMs are amenable to resection at time of diagnosis. The only of those is alcohol injection but this features a role limited to small hepatoma. Cryotherapy and radiofrequency ablation are going to be discussed intimately. Despite the increased resectability in advanced CLMs with two-stage hepatectomy, approximately 20% of patients may fail to travel through with the planned treatment. The speed of resectability had also expanded over the years due to the supply of higher chemotherapy agents permitting improved local disease control and down staging of tumor burden allowing subsequent resection. Post-operative hepatic functional reserve remains the most limitation to surgical resection, hence the attractive alternative of employing the adjunctive use of ablative therapies. There are multiple methods of percutaneous imaging-guided ablation. The appliance of cryotherapy isn't limited to lesion ablations but also could also be wont to treat suboptimal or involved margins of resection in patients precluded from extended resections. Long-term data following thermal ablation are scarce. Till date, the prevalence of either thermal ablative method remains unclear and further sizeable comparative studies would be required to work out this.

High Impact List of Articles

Relevant Topics in