Medical Case Reports

The study of role of magnesium sulphate vs. Diazepam in eclampsia

International Conference on Physicians, Surgeons and Case Reports
November 19-20, 2018 Paris, France

Tariq Masood Khan

Lady Willingdon Hospital Lahore, Pakistan

Posters & Accepted Abstracts: Med Case Rep

DOI: 10.21767/2471-8041-C2-006

Abstract

Eclampsia is a life threatening condition with highest mortality and morbidity characterized by uncontrolled hypertension, unconsciousness fits albumin urea in the setting of preeclampsia.

Study: An extensive elaborative study carried out from 2005 to 2009, to study the therapeutic and prophylactic role of magnesium sulphate and Diazepam in Eclampsia.

Aim: To study the role of magnesium sulphate (MgSO4) vs. Diazepam in reducing maternal mortality ratio (MMR), neonatal mortality rate (NMR) in Eclampsia.

Study Design: This was a comparative study. Total 500 patients of fulminant pre-eclampsia /eclampsia including booked/ unbooked patients attending Lady Willingdon Hospital were admitted, evaluated, assessed and put on MgSO₄ vs. Diazepam divided in two groups. The results were compared which showed of MgSO4 has superior efficacy compared to Diazepam in improving overall mortality and morbidity in Eclampsia.

Materials & Methods: Total 500 patients of Eclampsia were admitted and studied in Unit-2 Lady Willingdon Teaching Hospital of King Edward Medical University Lahore managed in ICU according to a specially design proforma, protocol and were given MgSO4 and Diazepam for control of fits, Hydralazine, Labetalol and Isoket infusions for lowering blood pressure (MgSO₄) A+B. Diazepam, with multidisciplinary involvement divided in two groups, compared and followed up.

Results: In Group A, there were 20 mothers and in Group B, 40 mothers died. It was observed that maternal mortality was significantly higher in Group B women as compared to that of Group A. i.e. (p-value=0.005).

Conclusion: The comparative study and of role of MgSO₄ vs. Diazepam in reducing mortality, morbidity in maternities, neoneties, efficacy showed the superiorness of magenesium sulphate as compared to Diazepam without any doubt.

Biography

E-mail: tmkhan58@hotmail.com