Journal of Emergency and Internal Medicine

Risk of diabetes mellitus in patients in using different types of hypnotics: A population-based cohort study

Joint Event on 8^th Edition of International Conference & Exhibition on Pain Management, Physiotherapy & Sports Medicine & 9^th Edition of International Conference on Internal Medicine & Patient Care
March 18-19, 2020 London, UK

Jin-Lin Chiu, Gwo-Ping Jong, Bo Yang and Hung-Yi Chen

China Medical University, Taiwan-ROC
Chung Shan Medical University Hospital, Taiwan-ROC
China Medical University Hospital, Taiwan-ROC
China Medical University Beigang Hospital, Taiwan-ROC

Posters & Accepted Abstracts: J Emerg Intern Med

Abstract

One tenth of Taiwanese suffer from chronic insomnia according to the research from Taiwan Society of Sleep Medicine in 2019. Research shows that the prevalence of Benzodiazepines drug use increased from 3.0% in 1997 to 3.3% in 2004. In Taiwan, the mortality rate of diabetes mellitus is among the top five causes of death. A study shows that the use of hypnotics is associated with abnormal blood glucose other research indicated sleep quality and quantity are the risk of new onset diabetes mellitus. Therefore, the study aims to investigate the relationship between hypnotics and newonset diabetes mellitus. The retrospective population-based cohort study was conducted to investigate the relationship between the hypnotic use and new-onset diabetes mellitus from National Health Insurance Research Database (NHIRD). The study used statistical methods Cox proportional hazard model and Kaplan-Meier survival curve. A total of 263,484 people were tracked from 2004 to 2013 between the ages from 40 to 90 after screening data by exclude criteria. The results of the study found that there were statistically significant difference between the cumulative medication duration ≥180 days (HR=1.780; 95% CI, 1.725-1.827), the use of benzodiazepines (HR=1.739; 95% CI, 1.680-1.800) and Z-drug (HR=1.706; 95% CI, 1.585-1.838), related to the new-onset diabetes.

Biography

Jin-Lin Chiu has completed her Master’s Program of Pharmaceutical Manufacture from China Medical University in Taiwan. She has expertise in statistical analysis of epidemiology and clinical pharmacology. She is also a teaching assistant and research assistant in Pharmacy department.