Nano Research & Applications

Nanoscale engineering of plasmonic materials for biosensing and bioimaging

Virtual Meet on Nanotech Forum 2021
October 29-30, 2021 | Webinar

Fang Xie

Imperial College London, UK

ScientificTracks Abstracts: Nano Res Appl

Abstract

Early diagnosis plays an increasingly significant role in current clinical drive. Detection, identification, and quantification of low abundance biomarker proteins form a promising basis for early clinical diagnosis and offer a range of important medical benefits. Amplification of light from NIR fluorophores by coupling to metal nanostructures, i.e. Metal Induced Fluorescence Enhancement (MIFE), represents a promising strategy for dramatically improving the detection and quantification of low abundance biomarker proteins, and potentially increase already sensitive fluorescence-based detection by up to three orders of magnitude. The amplification of the fluorescence system is based on interaction of the excited fluorophores with the surface plasmon resonance in metallic nanostructures. The enhanced fluorescence intensity due to the existence of metal nanostructures makes it possible to detect much lower levers of biomarkers tagged with fluorescence molecules either in sensing format or for tissue imaging. The first part of my talk will focus on some recent developments of plasmonic metal nanostructures by both “top-down” and “bottom up” methods. I will then discuss the prepared plasmonic nanostructures in the applications of biosensing and bioimaging, with the emphasis on plasmonic enhancement towards NIR I and NIR II regions.

Biography

Fang Xie is a Senior Lecturer at Department of Materials, Imperial College London. She is also Deputy Director for MSc in Advanced Materials. She has expertise in functional nanomaterials including metal, semiconducting, and oxide nanomaterials synthesis, as well as the applications of the functional materials in energy and life sciences. Her current research interests include plasmonic nanostructures for efficient light harvesting for solar cells and solar fuels, as well as in ultrasensitive biosensing and Bioimaging applications. She is member of Royal Society of Chemistry and serves as associate editor for Materials Today Advances and Nature Scientific Reports. She has over 60 publications including five patents. She has also delivered over 10 keynote and invited talks in the international conferences.