Isolation, structural elucidation and bioactivity studies of leaf extract of Vernonia amygdalina

Muluye Melak Zenebe

doi:10.21767/2472-1123-C5-015

Isolation, structural elucidation and bioactivity studies of leaf extract of Vernonia amygdalina

8^th Edition of International Conference on Chemistry Education and Research
August 27-28, 2018 Zurich, Swit zerland

Muluye Melak Zenebe

University of Gondar, Ethiopia

Posters & Accepted Abstracts: J Org Inorg Chem

DOI: 10.21767/2472-1123-C5-015

Abstract

Vernonia amygdalina (VA) is a tropical African plant of the Asteraceae family and is occasionally cultivated for its medicinal uses, which include as a treatment for diarrhea, skin wounds, fever mastitis and warms infection. The aim of this study is to isolate and elucidate the structure of some of the chemical constituents from the leaf of Vernonia amygdalina and its bioactivities. Methanol extract of Vernonia amygdalina, after repeated chromatography led to the isolation of a different compound, one of this compound (MM-4) is partially characterized based on the spectral data (IR, 1H NMR, 13C NMR, and DEPT) and extracts from Vernonia amygdalina have been shown to have antimicrobial activity.