Abstract

The concept of mesenchymal stem cells (MSC) being proposed as a medicinal signaling agent is based on the fact that cells are not single molecular agents. MSCs, which more appropriately may be called ‘Living Drug’ molecules, are adaptive agents capable of complex functions involving many bioactive factors. These multi-potent cells may be considered injury-specific drug stores that home to the site of injury and secrete considerable levels of immunomodulatory and trophic factors.