The accessibility of genomic information gives a chance to comprehend parasite science and to recognize new medication applicants against dismissed infections influencing a large number of individuals around the world. Practical comment of genomes, transcriptomes and anticipated proteomes is one of the significant difficulties in sequencing ventures. We address this test by applying a developmental structure to the translation of arrangement information. Our exploration ventures have been centered around the investigations of unmistakable protein families in helminths (Schistosoma and others) and protozoans (Leishmania, Trypanosoma, and Plasmodium), which cause a wide scope of sicknesses. These protein families incorporate for the most part protein kinases, protein deacetylases, and proteases. Potential homologues in the anticipated proteomes of chose taxa are recognized by utilizing concealed Markov model profiles. Transformative connections of protein groupings are recreated by two character-based strategies (Bayesian deduction and most extreme probability).