Abstract

Foot disease influences almost 6% of individuals with diabetes and incorporates disease, ulceration, or demolition of tissues of the foot. It can debilitate patients' personal satisfaction and influence social interest and vocation. Somewhere in the range of 0.03% and 1.5% of patients with diabetic feet require a removal. A diabetic foot is afoot that shows any pathology that outcome specifically from diabetes mellitus or any long haul (or "interminable") complexity of diabetes mellitus. The presence of a few trademark diabetic foot pathologies, for example, disease, diabetic foot ulcer, and neuropathic osteoarthropathy are called diabetic foot disorder. Because of the fringe nerve brokenness related to diabetes (diabetic neuropathy), patients have a lessened capacity to feel torment. This implies minor wounds may stay unfamiliar for quite a while. Individuals with diabetes are likewise in danger of building up a diabetic foot ulcer. Research gauges that the lifetime rate of foot ulcers inside the diabetic network is around 15% and may progress toward becoming as high as 25%. In diabetes, fringe nerve brokenness can be joined with fringe corridor ailment (PAD) making poor blood flow the furthest points (diabetic angiopathy). Around half of the patients with a diabetic foot, the ulcer has existing together PAD. Where wounds set aside a long opportunity to mend, contamination may set in, and bring down appendage removal might be essential. Foot disease is the most well-known reason for non-horrible removal in individuals with diabetes. Honey’s rapid anti-inflammatory activity soon suppresses the inflammation so that the raised amount of exudate decreases, which decreases swelling, pain, and absorption of edema fluid. Also, it controls hypertrophic scarring resulting in less scar tissue. It improves circulation and supplies more oxygen and nutrient to facilitate tissue repair and healing. The aims of the present study were to develop an ointment containing active antimicrobial honey and to evaluate the efficacy of such newly formulated ointment by conducting clinical trials on patients suffering from Diabetic foot ulcers. In the present clinical trial, 20 male and 05 female patients with diabetic foot ulcers were. A honey ointment containing 20% active antimicrobial honey was applied three times per day for the treatment of wounds. Diabetic foot ulcer cases healed 95% within the mean healing time of 20 days (range 8– 40 days). The significantly achieved results of honey against wound infecting bacteria are conducive and led to the development of a new honey ointment formulation. The promising evidence of clinical trials suggests the continued application of honey ointment as the natural alternative product in all phases of, diabetic foot ulcers