Outbreaks of foodborne disease remain a major public health and food safety concern. By assuring the safety of food before it is distributed to the public, customers can be protected from foodborne infections. The development of quick, competent, and reliable technologies for direct detection and identification of foodborne pathogens is urgently needed. Traditional methods for detecting bacterial infections and toxins are time-consuming and labor-intensive, necessitating the use of specialized apparatus and skilled workers. To overcome these limitations, an immediate need for the development of some edge alternative succeeded with an analytical approach. A biosensor-based process is robust state-of-art for broad practical applications in diverse pathogenic bacteria detection. For the quick detection of food-borne diseases, microbe-based biosensing technologies such as optical, surface plasmon resonance (SPR), amperometric, potentiometric,whole-cell, electrochemical, impedimetric, and piezoelectric have been used. These methodologies will be discussed, as well as future developments in biosensor research activities, in order to pave the road for fresh and nutritious food proposals.