ISSN : 0976-8505
Bharath K*
Department of Chemistry, Utkal University, Bhubaneswar, Odisha, India
Received date: January 03, 2022, Manuscript No. IPDCS-22-12797; Editor assigned date: January 05, 2022, PreQC No. IPDCS-22-12797 (PQ); Reviewed date: January 17, 2022, QC No. IPDCS-22-12797; Revised date: February 03, 2022, Manuscript No. IPDCS-22-12797 (R); Published date: February 15, 2022, DOI: 10.36648/0976-8505.13.2.8
Citation: Bharath K (2022) A Brief Note on Biochemistry. Der Chem Sin Vol.13 No.2: 008.
The study of chemical processes within and pertaining to live beings is known as biochemistry or biological chemistry. Biochemistry is organised into three fields: structural biology, enzymology, and metabolism. It is a sub-discipline of both chemistry and biology.
Biochemical methods and study are being used to explore and develop almost every aspect of the biological sciences. Biochemistry focuses on understanding the chemical base that allows biological molecules to give rise to the activities that occur within live cells and between cells, which has a lot to do with the form and function of tissues and organs. Biochemistry is intimately linked to molecular biology, which is the study of biological phenomena' molecular mechanisms. The structures, bonds, activities, and interactions of biological macromolecules such as proteins, nucleic acids, polysaccharides, and lipids are the focus of most of biochemistry. They give cells their structure and conduct many of the processes that make life possible.
The chemistry of the cell is also influenced by small molecule and ion processes. These can be biological or inorganic. Metabolism is the process by which cells use chemical reactions to extract energy from their surroundings. Biochemistry's findings are mostly used in medicine, nutrition, and agriculture. Biochemists study disease causes and treatments in medicine.
Approximately a half-dozen chemical components are required for various forms of biological life. The majority of uncommon elements on Earth aren't required for life, while only a few common elements aren't utilised. Although most organisms have similar element requirements, there are a few distinctions between plants and animals. Bromine is used by ocean algae, while land plants and animals do not appear to require it.
Some plants, however, do not require salt. Plants and animals both require boron and silicon, although animals may not. Only six elements make up over 99 percent of the mass of living cells, including those in the human body: carbon, hydrogen, nitrogen, oxygen, calcium, and phosphorus. Humans require lower amounts of the six main elements that make up the majority of the human body.
Carbohydrates, lipids, proteins, and nucleic acids are the four primary groups of molecules in biochemistry. Many biological compounds are polymers: monomers are relatively small macromolecules that are joined together to form larger macromolecules known as polymers in this language. Dehydration synthesis is a process that occurs when monomers are joined together to form a biological polymer. Larger complexes of macromolecules can be formed, which are frequently required for biological activity.
Carbohydrates serve two important functions: energy storage and structure. Carbohydrate is one of the most prevalent sugars, but not all carbohydrates are sugars. Carbohydrates store energy and genetic information, as well as play vital roles in cell-to-cell connections and communications, and there are more of them on Earth than any other known type of biomolecule. Through a dehydration reaction in which a molecule of water is released, two monosaccharides can be linked together by a glycosidic or ester bond to form a disaccharide. Hydrolysis is the reversible reaction in which a disaccharide's glycosidic link is broken into two monosaccharides.
An oligosaccharide is formed when a number of monosaccharides are linked together. These compounds are commonly utilised as markers and signals, but they can also be used for other purposes. A polysaccharide is made up of several monosaccharides linked together. They can be branched or connected together in a single long linear chain. cellulose and glycogen are two of the most common polysaccharides, both of which are made up of repeated glucose monomers. Glycogen is employed as a type of energy storage in animals, while cellulose is a key structural component of plant cell walls. Sugar can be classified as either reducing or non-reducing.
A carbon atom at the reducing end of a carbohydrate can be in equilibrium with an open-chain aldehyde (aldose) or keto form (ketose). The free hydroxy group of the pyranose or furanose form is exchanged with an OH-side-chain of another sugar when monomers are joined at this carbon atom, generating a complete acetal. This prevents the chain from being opened to the aldehyde or keto form, making the changed residue non-reducible. The glucose moiety of lactose has a reducing end, but the galactose moiety forms a complete acetal with the C4-OH group of glucose. Because of full acetal synthesis between the aldehyde carbon of glucose and the keto carbon of fructose, saccharose does not have a reducing end.
Lipids include waxes, fatty acids, fatty-acid derived phospholipids, sphingolipids, glycolipids, and terpenoids, and are a catch-all term for relatively water-insoluble or nonpolar chemicals of biological origin. Some lipids are open-chain aliphatic molecules with a linear structure, whereas others have a ring structure. Some of them are fragrant, while others aren't. Some are adaptable, while others are inflexible. One molecule of glycerol is generally joined with additional molecules to form lipids. One molecule of glycerol and three fatty acids make up triglycerides, the most common type of bulk lipid. In this situation, fatty acids are the monomer, and they might be saturated or unsaturated.
In addition to being predominantly nonpolar, most lipids exhibit some polar properties. The majority of its structure is nonpolar or hydrophobic, which means it does not interact well with polar solvents such as water. Another component of their structure is polar or hydrophilic, which means they prefer to be around polar solvents like water. As a result, they are amphiphilic compounds. The polar group in the case of cholesterol is a mere –OH (hydroxyl or alcohol). Lipids are a necessary component of our diet. Fats make up the majority of cooking and eating oils and milk products, such as butter, cheese, and ghee.
Polyunsaturated fatty acids abound in vegetable oils. Lipid-containing foods are digested by the body and broken down into fatty acids and glycerol, which are the fats and lipids' final breakdown products. Lipids, particularly phospholipids, are employed in a variety of pharmaceutical products as co-solubilizers or as drug carrier components.