Wound healing property of bioactive compound from actinomycetes

The main objective of this work was to find out the angiogenic or wound healing property of the bioactive compound from actinomycetes isolated from mangrove soil. Five potential actinomycetes strains were isolated from mangrove soil and screened for bioactive compounds. Bioactive compounds from actinomycetes exhibited an effective antibacterial activity against the both Gram positive and Gram negative bacterial strains, Bacillus, Pseudomonas, Staphylococcus and E.coli. The wound healing property of bioactive compounds was carried out by Chorio Allontoic Membrane assay in embryonated egg. The bioactive compounds extracted from Actinomycetes strain (GN2) showed an excellent wound healing property in embryonated egg.

Author(s): A. Janardhan, A. Praveen Kumar, M. Reddi Pradeep, DVR. Sai Gopal and G. Narasimha

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