Wound healing activity of topical application form based on herbomineral formulation

The traditional Indian medicine—Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. Mimusops elengi (Sapotaceae) commonly called as ‘Bakul’ in India. In Ayurveda, M. elengi has been reported to be used for arresting bleeding of gums and preparation of a lotion for sores and wounds. Zinc is a trace mineral, a component of many enzymes, including DNA and RNA polymerases, Matrix metalloproteinase ((MMPs) and is also required for protein synthesis, DNA synthesis, mitosis, and cell proliferation. Many of these zinc-dependent processes are required for wound healing, such as collagen synthesis and cell division. Consequently, zinc forms one of essential nutrients for normal wound healing. In the present study Yashad Bhasma is used as a source of zinc. There was no scientific evidence justifying the use of Mimusops elengi bark along with Yashad Bhasma for treatment of wound, therefore the present study was aimed at evaluation of wound healing activity of the plant (Bark) in combination with Yashad Bhasma in Excision, Incision and Estimation of biochemical marker models.

Author(s): Sushil S. Pimpare, Yogesh T. Sonawane, Chetan A. Chaudhari, Lalit P. Sali, Naveenkumar P. Jain and Chhaya H. Gadgoli*

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