Utilizing Pacific Biosciences sequencer information to examine DNA structures progressively polymerase energy

The presence of a DNA structure other than the authoritative twofold helix can be shown by the delay of DNA polymerase. We depict a technique for deciding how polymerase stopping in Pacific Biosciences sequencer peruses is identified with DNA structure. The Pacific Biosciences sequencer utilizes optics to notice a polymerase and its association with a solitary DNA particle continuously, giving an original strategy to identifying potential elective DNA structures. Stopping DNA polymerase is a typical strategy for researching DNA successions with the possibility to frame elective DNA constructions, and Pacific Biosciences information has recently been utilized to quantify polymerase stopping at a slipped strand structure.

Author(s): Maria Gabriella

Abstract | PDF

Share This Article