UPLC-MS Quantification and Anticancer Potential of Ximenia Americana
Hydro-Acetonic Crude Extract Leaves

Kabran GRM; Mamyrbekova-Bekro JA; Pirat JL; Lecouvey M; Sainte-Cathérine O; Sommerer N; Verbaere A; Meudec E; Békro YA

Abstract

UPLC-MS Quantification and Anticancer Potential of Ximenia Americana Hydro-Acetonic Crude Extract Leaves

Ximenia americana is a plant of the Ivorian pharmacopeia used in the treatment of various diseases. The present study aims firstly, to quantify by UPLC-MS some phenolic compounds contained in Ximenia americana and secondly, to evaluate its cytotoxic potential against 6 cancerous cells lines. UPLC-MS quantitative analysis revealed the presence of flavonoids (13%), gallotannins (5%), phenolic acids (0.7%), ellagic acid (0.3%) and an abundance of condensed tannins (81%). The cytotoxicity study indicated an antiproliferative behavior notable of this plant.

Author(s): Kabran GRM, Mamyrbekova-Bekro JA, Pirat JL, Lecouvey M, Sainte-Cathérine O, Sommerer N, Verbaere A, Meudec E, Békro YA

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