Objective and design: Prospective randomized trial to test the effectiveness of topical oxytocin gel Versus Hifu in improving vaginal atrophy in postmenopausal women. Patients and methods: A total of 50 postmenopausal women presenting with vaginal atrophy and who satisfied the inclusion and exclusion criteria were randomized into two groups each of 25 patients; they received intravaginal oxytocin gel or HIFU for one setting. Serum estrogen level, visual, colposcopy and histological vaginal examination were performed before and after treatment.
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