The Impact of Psychological Treatment on Catastrophization and Pharmacological Response in Chronic Migraine: A Single-Center Experience

Background: This study aimed to evaluate how pain catastrophizing, measured by the Italian Pain Catastrophizing Scale (PCS), influences clinical outcomes in chronic migraine patients. It employed a multidisciplinary approach, including psychological treatment.

Methods: Twenty-five outpatients from the SS. Antonio e Biagio e Cesare Arrigo headache clinic were randomly assigned Galcanezumab, Erenumab, or Fremanezumab. Over six months, their responses were assessed by measuring monthly migraine day reductions and improvements in quality of life using Headache Impact Test (HIT-6), Migraine Disability Assessment Score questionnaire (MIDAS) and Beck’s Depression Inventory (BDI) II scales for comorbid depression evaluation.

Results: We identified a robust correlation between HIT-6 and PCS, showing coefficients of 0.81 at T1 and 0.88 at T2. Additionally, we did not observe any other significant correlations.

Conclusion: This study seeks to elucidate the impact of a multidisciplinary approach, which includes psychological follow-up, on a specific clinical phenotype of chronic migraines characterized by a heightened tendency to catastrophize however, more extensive data are required.

Author(s): Federica Nicoletta Sepe1*, Claudia Lanni2, Daniele Michelis2 and Giacomo Lancia3

Abstract | Full-Text | PDF

Share This Article