Staphylococcus aureus is one of the most important nosocomial pathogens that as a significant pathogen causes various infectious diseases and can become a life-threatening pathogen so it can cause a wide range of clinical infections. At present, the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in some areas is around 72 to 90% Nose is the most common carrier for S. aureus [1]. Nasal carriers are at risk for S. aureus infections.In recent years, the increasing number of methicillin-resistant S. aureus (MRSA) infections and resistance to various antibiotics has been a major challenge for physicians [2, 3]. Also, the virulence factors and toxins produced by this bacterium are responsible for several infections, in which Pantone Valentine Leukocidin (PVL) and exfoliating toxins are most closely associated.
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