Synthesis, Spectral Characterization, Electrochemical Behaviour, In vitro Antimicrobial and DPPH Radical Scavenging Activities of Iron (II), Cobalt (II) Complexes with Imidazolyl Terpyridine

Imidazole terpyridine (L) and its Fe(II), Co(II) metal complexes were synthesized. IR, UV-vis, Mass, ¹HNMR, elemental analysis, electrical conductance and magnetic moments is techniques were applied for characterization. Cyclic voltammetry studies of Fe(II) and Co(II) complexes in DMSO show that the complexes able to stabilize low oxidation state of Fe(I) and Co(I). The complexes were evaluated for antimicrobial and DPPH radical scavenging activities. They showed varying degree of activity with the values between 28.95-97.36 μm in DPPH radical scavenging activity. These synthesized metal complexes were found to be less active than the ligand and standard for DPPH radical scavenging activity. The antimicrobial activities of the metal complexes were found to more active than the ligand and the antifungal activity of the ligand, Fe(II) complex are insensitive.

Author(s): G. Krishnaveni, M Seeni Mubarak, M Kiruthika, R Elayaperumal

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