Synthesis of heterocyclic metal complexes, structural design and their anti-microbial potentials

New Schiff bases were derived by the condensation of 3–Aldehydosalicylic acid with p-Toludine and p-anisidine in alcoholic medium, forming 2-hydroxy-3-[(p-tolylimino) methyl] benzoic acid (Scheme 1) and 2-hydroxy-3-[(4- methoxy phenylimino) methyl] benzoic acid (Scheme 2). The coordination complexes of bivalent metal ions such as Cu (II), Zn (II), Co (II), Cd (II) and Ni (II) with these ligands were synthesized at various pH ranges. Hence, the structural design of synthesized metal complexes reveals the different coordination at different pH-ranges. These complexes have been characterized on the basis of elemental analysis, FTIR spectra and 1HNMR spectra. The complexes were colored and stable in air, the ligands act as monobasic bidantate, dibasic tridentate and dibasic tetradentate in nature at different pH ranges and forms 1:1 and 1:2 complexes with metal ions. The ligands and their metal complexes have also been tasted for their antimicrobial behavior against various microorganisms and all the complexes have shown good antimicrobial activity.

Author(s): Basavaraj M. Kalshettya, Ramesh S. Ganib and Mallikarjun B. Kalashettic

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