ISSN : 0976 - 8688
Der Pharmacia Sinica
Abstract
Synthesis, isolation and use of a common key intermediate for calcium antagonist inhibitors
The compound (3) synthesized from Nitrobenzaldehyde, tertiary butyl acetoacetate and piperidine can be used as a common intermediate for the production of calcium channel blockers like Nicardipine hydrochloride (1) and Pranidipine hydrochloride (2) with high purity.
Author(s): Neelakandan K
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