Synthesis, characterization and biological studies of some transition metal complexes of hydrazone Schiff base ligand derived from of 2-quinolone and 1-phthalazine hydrazine hydrochloride

Mononuclear solid complexes of transitions metals Mn(II), Fe(III), Co(III), Ni(II), Cu(II) and Zn(II). were synthesized by using Schiff base hydrazone derived from 1-ethyl-4-hydroxy-2(1H)-quinolone and 1-phthalazine hydrazine hydrochloride. The ligand and complexes have been characterized by elemental analysis, UV-visible spectroscopy, FTIR, H1NMR, mass spectroscopy, magnetic susceptibility, conductivity and X-ray diffraction study. From analytical data the stoichiometry of the complexes has been found to be 1:2 (metal : ligand). The physicochemical study supports the octahedral geometry of all the complexes except Cu(II) having distorted octahedral geometry. The X-ray diffraction data suggests triclinic crystal system for all the metal complexes. The ligand functions as ONN tridentate preferred in the coordination producing octahedral complexes. The antimicrobial studies show the enhancement in the activity of ligand after complexation.

Author(s): A. A. Kachare, S. A. Kumbalpuri, S. G. Shankarwar and T. K. Chondhekar

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