Synthesis, characterization and biological screening of novel (E)-1-(3,5-bis(trifluoromethyl)phenyl) 3-(substituted)phenylprop-2-en-1-one

Tejas Vyas; Kiran Nimavat; Kartik Vyas; Kaushik Joshi

Abstract

Synthesis, characterization and biological screening of novel (E)-1-(3,5-bis(trifluoromethyl)phenyl) 3-(substituted)phenylprop-2-en-1-one

Synthesis of various Chalcones of (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one 3(a-o) from 3,5 Bis (trifluoromethyl)acetophenone and substituted benzaldehydes in presence of KOH. The structures of the synthesized compounds were confirmed on the basis of spectral and elemental analysis. The synthesized compounds were screened for antimicrobial activity.

Author(s): Tejas Vyas, Kiran Nimavat, Kartik Vyas, Kaushik Joshi

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