Synthesis, characterization and application of novel biopolymeric Schiff base from chitosan and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde

Schiff base of chitosan and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde was prepared by reaction of chitosan with 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde in the presence of acetic acid as a solvent. Some reaction parameters have been investigated such as temperature effect, time effect and mol ratio and optimize the product. The product has been ascertained by FT- IR spectroscopy. Antifungal activities of the Schiff base against Aspergillus niger (A. niger) and Penicillium were measured through the agar well diffusion method

Author(s): Amit B. Dholakia1, Jignesh B. Dholakiya2 and Devyani Y. Mehta1

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