Synthesis, characterization and antimicrobial activity of Cobalt(II), Nickel(II) and Zinc(II) complexes with azo ligand derived from 1-(4-amino phenyl) ethanone

The azo base of 1-(4-amino phenyl) ethanone and their complexes were synthesized and well characterized by elemental analysis, spectral studies, conductivity and magnetic measurements. All the complexes have lower molar conductance values, indicating their non-electrolytic nature. The synthesized ligands, along with their metal complexes were screened for their in-vitro antibacterial activity against Gram-negative (Escherichia coli) and a Gram-positive (Staphylococcus aureus) bacterial strains and for in-vitro antifungal activity against Candida albicans. The results of these studies revealed that all the compounds and their metal complexes showed significant antibacterial and antifungal potency.

Author(s): S. Karthikeyan, N. Sampath Kumar, R. Ebenezer, S. Chandra Mohan and P. Balasubramanian

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