Synthesis and photochemical investigation of 1,2-di(pyrimidine-2-yl)diazine

Pyrimidine is a prominent member of the diazine family of heterocycles and literature scanning revealed that it is found in nature as a component of nucleic acids nucleotides and corresponding nucleosides. The condensation reaction of a diketone and guanidine nitrate to form amine-functionalized pyrimidine and it was further oxidatively coupled with other unit to get the azo linked bis pyrimidine unit. Finally, it was further reduced with hydrazine to get titled compounds. The synthesized compounds were characterized by spectral techniques, viz. FT IR, 1H NMR and 13C NMR spectra. UV-irradiation study of the 2,2’-(Z)-diazene-1,2-diylbis-(4,6-dimethylpyrimidine) showed a reversible isomerization of the compound.

Author(s): S. Parvathy, A. Kalaiyarasi, P. T. Liji and B. R. Venkatraman

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