Syntheses, characterization of some transition metal complexes of bidentate schiff base and their antimicrobial activities

The solid complexes of Cu (II), Ni (II) and Co (II) were prepared from bidentate Schiff base. The Schiff base ligand synthesized from the condensation of P-nitrobenzaldehyde and 2-amino -4,6 dihydroxypyrimidine (L2) in alcohol medium. These metal complexes were characterized on the basis of their micro analytical data, molar conductance, magnetic susceptibility, IR, UV-Vis, 1H NMR, X-ray diffraction, therogravimetric analysis. The ligand and their metal complexes were screened for fungicidal activity against various fungi like Aspergillus niger, Penicillium chrysogenum, Fusarium moneliforme and Aspergllus flavus. and antibacterial activity against various bacteria likes Escherichia coli, Salmonellatyphi, Staphylococcus aureus, B.subtilis. The result indicated that the complexes exhibited good antifungal and antibacterial activities

Author(s): D. T. Sakhare1, T. K. Chondhekar2, V. L. Borde3 and A. G. Shankarwar3

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