Surgery is an Effective option for Patients with Newly Developed Advanced Breast Cancer

Breast cancer (BC) remains one of the most challenging problems in clinical oncology because it still has the highest incidence of all malignant tumors in women worldwide. A significant number of breast cancer patients worldwide (8.3%) and Russia in particular (11.5%) are first diagnosed in the fourth phase The doctors knows that the breast cancer occurs when some breast cells begin to grow abnormally. These cells divide faster than healthy cells do and continue to accumulate to form a mass . Cells may spread (metastasize) through your breast to your lymph nodes or other areas of your body. Breast cancer begins with cells in milk-producing ducts. Breast cancer may also begin in the glandular tissue called lobules or in other cells or tissues in the breast. Researchers have identified lifestyle, hormonal and environmental factors that could increase the risk of breast cancer.But it is unclear why people who do not have risk factors develop cancer, but other people with risk factors never do. Breast cancer is most likely caused by a complex interaction of your genetic makeup and your environment. There are many publications proving the feasibility of surgical treatment for some patients with metastatic BC. Till now, there is no strong understanding of the importance of cytoreductive surgery in treating BC dissemination. The most frequently discussed issue is the eligibility of patients for this treatment, as it is unclear what plays a crucial role in the selection process: localization of systemic therapy, metastasis, susceptibility to tumor characteristics or a combination of these factors

Author(s): A A Bozhok, E E Topuzov, A D Zikiryakhodzhaev, A S Sukhot’ko, Khaylenko V A, Shatova Yu S, Klimov N A and Paltuev R M

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