Studies on antibacterial activity of some medicinal plant against Human pathogenic Micro Organism

The bacteria organisms were isolated from drinking water ( Bacillus, Borchothrix, Clavibacter sp, Anguslobacter sp, and Brevi bacterium ). Selected Indian medicinal plants Strychnos nuxvomica and cassia angustifolia were selected for antibacterial studies . The solvents used for the extraction of plant roots were n- butanol, ethyl acetate and distilled water. The invitro antibacterial activity was performed by agar well diffusion method. The most susceptible Gram- Postive bacteria was Bacillus sp, Brevibacterium sp, and the most susceptible Gram-negative bacteria was Borchothrix sp, Clavibacter sp, and Ancylobacter sp. The extracts of plant Strychnos nuxvomica and cassia angustifolia inhibited the growth of the bacterial strains investigated. The most active extracts was compared with the standard antibiotics, pencillin, Streptomycin and Ampicillin 100mg/disc). The results obtained in the present study suggest that Strychnos nuxvomica and cassia angustifolia could be used in treating diseases caused by the test organisms. The results are discussed in detail.

Author(s): R. Mahalingam, R. Bharathidasan, V. Ambikapathy and A. Panneerselvam

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