Studies of Schiff base derived from Sulphadiazine and 2-hydroxy, 1- napthaldehyde / benzoyl acetone for gravimetric determination of the Cu(II)

Compounds containing the sulphonamide group have long been used as drugs for diseases like cancer, tuberculosis, diabetes, malaria and leprosy etc. It has now been observed that some of these drugs show increased biological activity when administered in the form of metal complexes. The present works deals with the synthesis and preliminary characteristics of various ligands. Here all the ligands are Schiff bases. Schiff bases derived by the condensation 2-hydroxy,1-napthaldehyde or benzoylacetone with Sulphadiazine. After synthesis of such Schiff bases as ligands, Cu(II) ion introduced with them by chelation. The chemical and physical properties of metal chelates will be evaluated

Author(s): Dasharath P. Patel, Shailesh P. Prajapati, Arjun K. Rana and Pankaj S. Patel

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