Stem cell therapy in avoiding pathogenesis of Rheumatoid Arthritis

Rheumatoid Arthritis is an inflammatory disease of joints. It is a chronic autoimmune disease I.e.; it's means when a person's own immune system mistakenly attacks own body's tissue. Rheumatoid Arthritis can not only damage joints of a person's body but also can damage a wide range of body's system like eyes, skin, heart, lungs blood vessels. Rheumatoid Arthritis serves inflammation in joints (generally small joints like the one joining figures to hands) which can ultimately lead to bone erosion or physical disabilities. To treat this autoimmune inflammation disease – modifying antirheumatic drugs (DMARDS) are used. However only 70% of the patients dealing with RA get satisfactory results. Mesenchymal stomal/ stem cells (MScs) are cells which have tissue repairing and immuno- modulatory properties. They are being used for managing RA. MScs are adult stem cells and multipotent i.e., present in many tissues. These cells can renew on their own and can also differentiate into numerous tissues like fat cells, muscles

Author(s): Riya Dubey

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