RELATIONSHIP BETWEEN POLYMORPHISM SCN1A AND POLYTHERAPY IN EPILEPTIC PATIENT: PILOT STUDY

Background: Despite the advances in the pharmacological treatment of epilepsy, polytherapy anti-epileptic drug still remains challenging. Understanding of the pharmacogenetic causes is critical to predict drug response hence providing a basis for personalized medications. SCN1A genes belong to a family of genes that provide instructions for making sodium channels that important for antiepileptic drug (AED) target

Aims: The purpose of this study was to investigate relationship between polymorphism SCN1A rs 2298771  and polytherapy in epileptic patient

Methods: In total, 34 adult patients with epilepsy were consecutively recruited during routine outpatient

Author(s): Dr. Atitya Fithri Khairani

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