Reduced residual urine volume is independently associated with left ventricularsystolic and diastolic dysfunction in Congolese patients on maintenance hemodialysis: A post hoc analysis.

Objective

Cardiac dysfunction, valvular calcification (VC) and decrease residual renal function are known independently associated with cardiovascular complications and all-cause mortality in chronic hemodialysis. But, little is known whether residual urine volume (RUV) may contributed to occurrence of cardiac dysfunction or VC. This study aimed to investigate whether RUV was associated with VC, left ventricular systolic and diastolic dysfunction in hemodialysis in Kinshasa between March 2016 and October 2017.

Methods

A cross sectional study including patients on maintenance hemodialysis for at least 6 months in 4 hd centers. vc were defined as a luminous echo of more than 1 mm on 1 or more cusps of the valve, lvsd (lvef <55%) and lvdd (e / a Ë? 1 or Ë? 2, e / a between 1-2 with e / e 'Ë?13) were investigated by doppler echocardiography performed 24 hours after the hd session. urine collection was performed during the interdialytic period. the determinants were investigated by logistic regression analyses.

Results

71 patients (mean age 51.7 ± 16.6 years, 38 with reduced RUV). The determinants associated with: VC were HT (p=0,026), age > 60 years (p=0,012), tobacco (p=0,039), hyperphosphoremia; LVSD: HT (p= 0.016), hyperphosphoremia (p=0.003); RUV (p=0,017); ABI (p=0.025) and LVDD: diabetes mellitus (p= 0.025), tobacco (p=0.015), SBP (p=0.020) and RUV (p=0,019).

Conclusion

In this study, reduced RUV is independently associated with systolic and diastolic dysfunction as opposed to VC.

Author(s): Yannick Mompango Engole

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