Preliminary Phytochemical Studies and Evaluation of Antibacterial Activity of Psoralea corylifolia Seed Extract

Present study aims to evaluate antibacterial efficacy of Bakuchi (Psoralea corylifolia) seed extracts prepared in two different solvents. Antibacterial assay was performed by agar well diffusion method against Gram positive skin pathogens, like Staphylococcus aureus, Staphylococcus epidermidis Pseudomonas aeruginosa and Gram negative skin pathogens, which included Klebsiella  pneumoniae, Proteus mirabilis, Proteus vulgaris and Escherichia coli. Bakuchi seed extract in methanol and diethyl ether exhibited broad spectrum antibacterial activity against skin pathogens, however comparatively bakuchi seed extract in methanol was found to be more promising with maximum zone of inhibition against K. pneumoniae with zone of inhibition 21mm in diameter and the minimum inhibitory concentration (MIC) 2.5mg/ml. These results confirmed the potential of the Bakuchi seed extract in the development of ayurvedic topical skin formulations.

Author(s): A.Borate, A. Khambhapati, M. Udgire, D. Paul and S. Mathur

Abstract | PDF

Share This Article