Phytochemical Analysis and Assessment of In-vitro Anthelmintic Activity of Cassia auriculata Linn leaves

Three different extracts namely Ethanol, Chloroform, Petroleum ether of Cassia auriculata Linn (Family: Caesalpiniaceae) leaves were screened for their phytochemical composition. The phytochemical studies of Cassia auriculata leaves show the presence of alkaloids, tannins flavonoids, glycosides, saponins along with proteins. Three extracts viz. Petroleum ether, Methanol and Chloroform extracts of Cassia auriculata leaves were investigated for the anthelmintic activity against earthworms [Megascoplex konkanensis]. Three concentrations [20, 40, 60mg/ml] of each extract were studied which included the determination of time of paralysis and time of death of earthworms. Albendazole [10 mg/ml] was used as standard drug and distilled water containing 2% Tween 80 was used as control. All the extracts exhibited dose dependent anthelmintic activity. The decreasing order of activity of extracts was assessed to be Methanol, Petroleum ether, and Chloroform.

Author(s): Sachin Chaudhary, and Amit Kumar

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