All Recent species of the American genus Macrocypraea are analyzed phylogenetically based on phenotypic features. The database was inserted in a wider phylogeny on Cypraeoidea previously published. The result is (((M. cervus (M. cervinetta (M. mammoth M. zebra))) Cypraea tigris) remaining Cypraeoidea). The monophyly of the genus us supported by four synapomorphies, and the proximity with C. tigris (among the anatomically known species) is demonstrated. The result is compatible with the subgeneric division Lorenzicypraea for M. cervus and Macrocypraea s.s. for remaining species.
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